Autophagy-Related IRGM Polymorphism Is Associated with Mortality of Patients with Severe Sepsis
نویسندگان
چکیده
منابع مشابه
Autophagy-Related IRGM Polymorphism Is Associated with Mortality of Patients with Severe Sepsis
OBJECTIVE Autophagy is the regulated catabolic process for recycling damaged or unnecessary organelles, which plays crucial roles in cell survival during nutrient deficiency, and innate immune defense against pathogenic microorganisms. Autophagy has been also reported to be involved in various conditions including inflammatory diseases. IRGM (human immunity-related GTPase) has an important func...
متن کاملCommon Genetic Variant of insig2 Gene rs7566605 Polymorphism Is Associated with Severe Obesity in North India
Background: Obesity is a very common disorder resulting from an imbalance between food intake and energy expenditure, and it has a substantial impact on the development of chronic diseases. The aim of this study was to examine the association of INSIG2 (rs7566605) gene polymorphism with obesity and obesity associated phenotypes in North Indian subjects. Methods: The variants were investig...
متن کاملUnderweight is associated with mortality in patients with severe sepsis and septic shock
Methods A retrospective analysis of prospectively collected database of patients with severe sepsis and septic shock was performed. We classified the patients into four groups according to the basic criteria of the World Health Organization (WHO) guidelines as follows, underweight, < 18.5; normal, 18.5-24.99; overweight, 25-29.99; obesity, ≥ 30 kg/m, respectively. The multivariate logistic regr...
متن کاملSocioeconomic Factors Associated With Mortality Rate Caused by Severe Stroke
Background: Stroke is one of the most important causes of disability-adjusted life years lost. Low socioeconomic status is associated with increased stroke-related morbidity and mortality. Objective: This study aimed to investigate in-hospital mortality rate caused by severe cases of ischemic and hemorrhagic stroke and its relationship with patients’ socioeconomic status. Materials and Method...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: PLoS ONE
سال: 2014
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0091522